Skip to main content

Publication List

*Undergraduate co-authors

  1. Ye M*.; Chen, E*. C.; Pfeil, S. H.; Martin, K. N.; Atrafi, T.*; Yun, S*.; Martinez, Z*.; Yatsunyk, L. A. Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad Bioorg. Med. Chem. 2023, 77 https://doi.org/10.1016/j.bmc.2022.117112
  2. Li K.*, Yatsunyk L. A., Neidle S. Machine learning shows torsion angle preferences in left-handed and right-handed quadruplex DNAs, Biophysical J., 2022, doi.org/10.1016/j.bpj.2022.08.021.
  3. Beseiso, D*.; Chen, E. V*.; McCarthy, S. E.; Martin, K. N.; Gallagher, E. P*.; Miao, J.; and Yatsunyk, L. A. “The First Crystal Structures of Hybrid and Parallel Four-Tetrad Intramolecular G-Quadruplexes” Nucleic Acids Res., 2022, 50, 2959–2972
  4. Li, K.*; Yatsunyk, L. A.; Neidle, S. "Water spines and networks in G-quadruplex structures." Nucleic Acids Res. 2020, 49(11), 519-528
  5. Lin, L. Y*.; McCarthy, S.; Powell, B. M.*; Manurung, Y.*; Xiang I. M.*; Dean, W. D.; Chaires, B.; Yatsunyk, L. A. "Biophysical and X-ray structural studies of the (GGGTT)3GGG G-quadruplex in complex with N-methyl mesoporphyrin IX.” PLOS ONE, 2020, 15(11), e0241513
  6. ​​​​​Yett, A.*; Lin L. Y.*; Beseiso, D.*; Miao, J.*; and Yatsunyk, L. A. "N-methyl mesoporphyrin IX as a highly selective light-up probe for G-quadruplex DNA." J. Porphyr Phthalocya, 2019, 23, 1195-1215. Contribution to Women in Porphyrin Sciences Special Issue. (equal contributions of the authors)
  7. Falabella, X. M.; Kolesar, J. E.; Wallace, C,; de Jesus, D., Sun, L.; Taguchi, Y. V.; C. Wang, C.; Wang, T.; Xiang, I. M.*; Alder, J. K.; Maheshan, R.; Horne, W.; Turek-Herman, J.*; Pagano, P. J.; St. Croix, C. M.; Sondheimer, N; Yatsunyk, L. A.; Johnson F.B.; and Kaufman B. A. "G-quadruplex dynamics contribute to regulation of mitochondrial gene expression." Sci Rep., 2019, 9, 5605-5621.​​​​​
  8. Naeem M. M.; Maheshan R.; Costford S. R.; Wahedi A.; Trajkovski M.; Plavec J.; Yatsunyk L. A.; Ciesielski G. L.; Kaufman B. A.; Sondheimer N. "G-Quadruplex Mediated Reduction of a Pathogenic Mitochondrial Heteroplasmy." Hum. Mol. Genet. 2019 PubMed PMID: 31261379.
  9. Sabharwal, N. C.*; Chen, J.*; Lee, J. H.*; Gangemi, C. M. A., D’Urso, A.; and Yatsunyk, L. A. Interactions between spermine-derivatized tentacle porphyrins and the human telomeric DNA G-quadruplex Int. J. Mol. Sci. 2018, 19, 3686.​​​​​​
  10. Shastri, N.; Tsai, Y-Ch.; Hile, S.; Jordan, D.*; Powell, B.*; Chen, J.*; Maloney, D.; Dose, M.; Lo, Y.; Anastassiadis, T.; Rivera, O.; Kim T.; Shah, S.; Borole, P.; Asija, K.; Wang, X.; Smith, K. D.; Finn, D.; Schug, J.; Casellas, R.; Yatsunyk, L. A.; Eckert, K. A.; and Brown, E. J. Genome-wide identification of structure-forming repeats as principal sites of fork collapse upon ATR inhibition .Mol. Cell 2018, 72, 222-238.e21.​​​​​​
  11. Guédin, A.; Lin, Y.*; Armane, S.; Mergny, J. -L.; Thore, S.; Yatsunyk, L. A. Crystal structure of G-rich sequence from the Dictyostelium discoideum genome: a four quartet G-quadruplex. Nucleic Acids Res. 2018, 46(10), 85297-5307 (equal contributions of two first authors)
  12. Kerkour A.; Marquevielle, J.; Ivashchenko, S.; Yatsunyk, L. A.,  Mergny, J.-L.; Salgado, G. “High-resolution 3D NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation” J. Biol. Chem. 2017, 292(19), 8082-8091
  13. Ruan, T.;* Davis, S.;* Powell, B.;* Harbeck, C.;* Habdas, J.; Habdas, P.; Yatsunyk, L. A. “Lowering the overall charge on TMPyP4 improves its selectivity for G-quadruplex DNA” Biochimie 2017, 132, 121-130.
  14. Boschi, E.; Davis, S.;* Taylor, S.;* Butterworth, A.; Chirayath, L. A.; Purohit, V.; Siegel, L. K.; Buenaventura, J.; Sheriff, A. H.; Jin, R.;* Sheardy, R.; Yatsunyk, L. A.; and Azam, M. Interaction of a Cationic Porphyrin and its Metal Derivatives with G-Quadruplex DNA J. Phys. Chem. B 2016, 120 (50), 12807-12819  (note, equal contribution of two last authors).
  15. Yatsunyk, L. A., Monchaud, D., and Sen, D. "Blending Quadruplexes and Bordeaux: a Grand Cru! The 5th International Meeting on Quadruplex Nucleic Acids, Bordeaux (France)" Cell Chemical Biology 2016, 23(3), 320-329.
  16. Sabharwal, N.C.;* Mendoza, O.; Nicoludis, J. M.;* Ruan, T.;* Mergny, J. -L. Yatsunyk, L. A. “IInvestigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA” J. Biol. Inorg. Chem. 2016, 21, 227-239.
  17. Dong, D. W.; Filipe Pereira, F.; Barrett S. P.;* Kolesar, J. E.; Cao, K.; Damas J. Yatsunyk, L. A.; Johnson F. B.; Kaufman, B. A. “Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints” BMC Genomics 2014, 15, 677. doi:10.1186/1471-2164-15-677.
  18. Yatsunyk, L. A.; Mendoza, O.; Mergny, J.-L. "Nano-oddities": Unusual nucleic acid assemblies for DNA-based nanostructures and nanodevices Acc. Chem. Res. 2014, 47, 1836-1844.
  19. Sabharwal, N. C.;* Savikhin, V.; Turek-Herman, J. R.;* Nicoludis, John M.;* Szalai, V. A.; Yatsunyk, L. A. "N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes" FEBS J. 2014, 281(7), 1726-1737.
  20. Renaud de la Faverie, A.; Guédin, A.; Bedrat, A.; Yatsunyk, L. A.; Mergny, J.-L. "Thioflavin T as a fluorescence light-up probe for G4 formation" Nucleic Acids Res. 2014.
  21. Yatsunyk, L. A.; Piétrement, O.; Albrecht, D.; Tran, P. L. T.; Renčiuk, D.; Sugiyama, H.; Arbona, J.-M.; Aimé, J.-P.; Mergny, J.-L. "Guided assembly of tetramolecular G-quadruplexes" ACS Nano 2013, 7, 5701 - 5710.
  22. Nicoludis, J. M.*; Miller, S.; Jeffrey, P.; Barrett, S. P.*; Rablen, P. R.; Lawton, T.; Yatsunyk, L. A. "Optimized end-stacking provides specificity of N-methyl mesoporphyrin IX for human telomeric G-quadruplex DNA" J. Am. Chem. Soc., 2012, 134 (50), 20446-20456.
  23. Yatsunyk, L. A.; Bryan, T.; Johnson, F. B. "G-ruption: The third international meeting on G-quadruplex and G-assembly" Biochimie 2012, 94, 2475-2483.
  24. Nicoludis, J. M*.; Barrett, S. P.*; Mergny, J.-L.; Yatsunyk, L. A. "Interaction of human telomeric DNA with N-methyl mesoporphyrin IX, NMM" Nucleic Acids Res. 2012, 40, 5432-5447.
  25. Bhattacharjee, A. J.*; Ahluwalia, K.*; Taylor, S.*; Jin, O.*; Nicoludis, J. M.*, Buscaglia, R.; Chaires, J. B.; Kornfilt, D. J. P.*; Marquardt, D. G. S.*, Yatsunyk, L. A. "Induction of G-quadruplex DNA structure by Zn(II) 5,10,15,20-tetrakis(N-methyl-4-pyridyl)porphyrin" Biochimie 2011, 93, 1297-1309.
  26. Smith, J. S.; Chen, Q.; Yatsunyk, L. A.; Nicoludis, J. M.*; Garcia, M. S.; Kranaster, R.; Balasubramanian, S.; Monchaud, D.; Teulade-Fichou, M.-P.; Abramowitz, L.; Schultz, D. C.; and Johnson, F. B. "Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae" Nature Structural and Molecular Biology 2011, 18, 478-485.
  27. Balasubramanian, R.; Smith, S. M.; Rawat S.; Yatsunyk, L. A.; Stemmler, T. L.; Rosenzweig, A. C. "Oxidation of methane by a biological dicopper center" Nature 2010, 465, 115-119.
  28. Banci, L.; Bertini, I.; Cantini, F.; Rosenzweig A. C.; Yatsunyk, L. A. "Solution Structure and Interaction with the Copper(I) Chaperone HAH1 of the Third and Forth Domain of Human ATP7B" Biochemistry 2008, 47, 7423-7429.
  29. Benitez, J. J.; Keller, A. M.; Ochieng, P.; Yatsunyk, L. A.; Huffman, D. L.; Rosenzweig, A. C.; Chen, P. "Probing Transient Copper Chaperone-Wilson Disease Protein Interactions at the Single-Molecule Level with Nanovesicle Trapping" J. Am. Chem. Soc. (Communication) 2008, 130, 2446-2447.
  30. Yatsunyk, L. A.; Easton, J. A.; Kim, L. R.; Sugarbaker, S. A.; Bennett, B.; Breece, R. M.; Vorontsov, I. I.; Tierney, D. L.; Crowder, M. W.; Rosenzweig, A. C. "Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli" J. Biol. Inorg. Chem. 2008, 13, 271-288.
  31. Yatsunyk, L. A.; Rosenzweig, A. C. "Copper(I) Binding and Transfer by the N-terminus of the Wilson Disease Protein" J. Biol. Chem. 2007, 282, 8622-8631.
  32. Weeler, K.; Nocek, J. M.; Cull, D.; Yatsunyk, L. A.; Rosenzweig, A. C.; Hoffman, B. M. "Dynamic Docking of Cytochrome b5 With Myoglobin and a-Hemoglobin: Heme-Neutralization 'Squares' and the Binding of Electron-Transfer-Reactive Configurations" J. Am. Chem. Soc. 2007, 129, 3906-3917.
  33. Teschner, T.; Yatsunyk, L. A.; Schünemann, V.; Hu, C.; Scheidt, W. R.; Walker, F. A.; Trautwein, A. X. "Low-Spin Ferriheme Models of the Cytochromes: Mössbauer Spectra of Six Crystalline Complexes Having Axial Ligand Plane Dihedral Angles Ranging from 0o to 90o" J. Am. Chem. Soc. 2006, 128, 1379-1389.
  34. Yatsunyk, L. A.; Dawson, A.; Carducci, M. D.; Walker, F. A. "Models of the Cytochromes: Crystal Structures and EPR Spectral Characterization of Low-Spin Bis-Imidazole Complexes of (OETPP)FeIII Having Intermediate Ligand Plane Dihedral Angles" Inorg. Chem. 2006, 45, 5417-5428.
  35. Yatsunyk, L. A.;Walker, F. A. "Synthesis and characterization of the iron(III) complexes of tetra-(b,b'-tetramethylene)tetraphenylporphyrin, (TC6TPP)FeCl and (TC6TPP)FeONO2" J. Porph. Phthal. 2005, 9, 214-228.
  36. Yatsunyk, L. A.;Ogura, H.;Walker, F. A. "Kinetics of Ring Inversion in Strongly Non-Planar Iron(III) Octaalkyltetraphenylporphyrinates" Inorg. Chem. 2005, 44, 2867-2881.
  37. Yatsunyk, L. A.;Shokhirev, N, V.; Walker, F. A."Magnetic Resonance Spectroscopic Investigations of the Electronic Ground and Excited States in Strongly Non-Planar Iron(III) Dodecasubstituted Porphyrins" Inorg. Chem. 2005, 44, 2848-2866.
  38. Cai, S.; Belikova, E.; Yatsunyk, L. A.;Stolzenberg, A. M.; Walker, F. A. "Magnetic Resonance Investigations of Mono-Oxo-Octaethylchlorinatoiron(III) Chloride and Its Bis-Imidazole Complex" Inorg. Chem. 2005, 44, 1882-1889.
  39. Teschner, T.; Trautwein, A. X.; Schünemann, V.; Yatsunyk, L. A.;Walker, F. A. "Low-Spin Ferriheme Models of the Cytochromes: Correlation of Molecular Structure with EPR and Mossbauer Spectral Parameters" Hyperfine Interactions 2004, 156/157, 285-291.
  40. Abajian, C.; Yatsunyk, L. A.;Ramirez, B. E.; Rosenzweig, A. C. "Solution Structure and Binding of Copper(I) by Yeast Cox17" J. Biol. Chem. 2004, 279, 53584-53592.
  41. Wernimont, A. K; Yatsunyk, L. A.;Rosenzweig, A. C. "Binding of copper(I) by the Wilson disease protein and its copper chaperone"J. Biol. Chem. 2004, 279, 12269-12276.
  42. Yatsunyk, L. A.;Walker, F. A. "NMR and EPR Spectroscopic and Structural Studies of Low-Spin, (dxz,dyz)4(dxy)1 Ground State Fe(III) bis-(tert-Butylisocyanide) Complexes of Dodecasubstituted Porphyrins" Inorg. Chem. 2004, 43, 4341-4352.
  43. 20. Yatsunyk, L. A.;Walker, F. A. "Structural, NMR, and EPR Studies of S = 1/2 and S = 3/2 Fe(III) Bis(4-Cyanopyridine) Complexes of Dodecasubstituted Porphyrins" Inorg. Chem. 2004, 43, 757-777.
  44. Yatsunyk, L. A.; Carducci, M. D.; Walker, F. A. "Low-Spin Ferriheme Models of the Cytochromes: Correlation of Molecular Structure with EPR Spectral Type" J. Am. Chem. Soc. 2003, 125, 15986-16005.
  45. Yatsunyk, L. A.;Walker, F. A. "19F Isotropic Shifts in Paramagnetic Iron(III) Octaethyltetraphenylporphyrinate and Tetraphenylporhyrinate Complexes of a Variety of Electronic Ground States: Implication for the Electron Configuration of Chloroiron Tri-(pentafluorophenyl)corrlate" Inorg. Chim. Acta 2002, 337, 266-274.
  46. Ogura, H.; Yatsunyk, L. A.; Medforth, C. J.; Smith, K. M.; Barkigia, K. M.;Renner, M. W.; Melamed, D.; Walker, F. A. "Molecular Structures and Magnetic Resonance Spectroscopic Investigations of Highly Distorted Six-Coordinate Low-Spin Iron(III) Porphyrinate Complexes" J. Am. Chem. Soc. 2001, 123, 6564-6578.
  47. Panchuk, O.; Savitsky, A.; Fochuk, P.; Nykonyk, Ye.; Parfenyuk, O.; Shcherbak, L.; Ilashcuk, M.; Yatsunyk, L. A.; Feychuk, P. "IV group dopant compensation effect in CdTe," J. Cryst. Growth 1999, 197, 607-611.
  48. Fochuk, P. M.; Panchuk, O. E.; Kochergan, V. I.; Yatsunyk, L. A. "High-temperature defects equilibria in Cu-doped CdTe" Neorg. Mater. 1996, 32, 1356-1358.