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Liliya Yatsunyk

A photo of Elizabeth Gallagher, Erin Chen, Sawyer McCarthy, Professor Yatsunyk, and Dana Beseiso over Zoom.

Department Overview

The Yatsunyk lab is looking for a new Research Assistant. For more information and how to apply, click the link here.

Our laboratory focuses on non-canonical DNA structures, G-quadruplexes, i-motifs, and tandem repeats. Such sequences are found at telomeres and oncogene promoters, among other regions. Small molecule ligands strongly affect fold and stability of non-canonical DNA and may act as anticancer therapeutics. We strive to determine the structural details of DNA and DNA-ligand complexes and understand the reasons behind structural diversity of DNA. Our favorite techniques include X-ray crystallography, UV-vis and fluorescence spectroscopies, circular dichroism (CD), fluorescence resonance energy transfer (FRET), gel electrophoresis, and synthetic work.   

If you are interested in working in the Yatsunyk lab:

  • send Liliya an email at lyatsun1 

  • stop by her office in SC 286 or the lab SC 285

Lab News 2021

Liliya, Erin, and Kevin gave talks at the ACS Spring 2021 Virtual Meeting and Exposition. Liliya presented "Structure of T. thermophila telomeric DNA alone and with N-methylmesoporphyrin IX, NMM" on April 5th, Erin presented "Elucidating the structure of a four-repeat Satellite III DNA sequence” on April 7th, and Kevin presented "Water networks in G-quadruplexes" on April 14th. 

Dana gave a poster presentation at the meeting, "Biophysical and structural characterization of Tetrahymena thermophila G-Quadruplexes alone and in complex with N-methyl mesoporphyrin IX."

The lab welcomed in the spring new students: Charlotte Pohl, Sara Yun, Tamanaa Atrafi, and Zahara Martinez.

Access our News Archives...

Enjoying beautiful weather and roses: Samantha Nyovanie, Ariana Yett '21, Hyun Kyung Lee '21, Deondre Jordan '19, Dr. Liliya Yatsunyk, Yanti Manurung '20,  Linda Lin '20

Enjoying beautiful weather and roses: Samantha Nyovanie, Ariana Yett '21, Hyun Kyung Lee '21, Deondre Jordan '19, Dr. Liliya Yatsunyk, Yanti Manurung '20,  Linda Lin '20

Summer 2018: Dr. Liliya Yatsunyk, Samantha Nyovanie, Arian Yett '21, Yanti Manurung '20, Hyun Kyung Lee '21, Linda Lin '20, Deondre Jordan '19

Summer 2018: Dr. Liliya Yatsunyk, Samantha Nyovanie, Ariana Yett '21, Yanti Manurung '20, Hyun Kyung Lee '21, Linda Lin '20, Deondre Jordan '19

Lab at t the 11th Frontiers in Chemistry & Biology Interface Symposium (University of Pennsylvania)

Spring 2018:  Linda Lin '20, Ariana Yett '21, Dr. Liliya Yatsunyk, Samantha Nyovanie, Barrett Powell '18 at the 11th Frontiers in Chemistry & Biology Interface Symposium (UPenn)

The lab at the Haverford URS 2017

Fall 2017:  Barrett Powell '18, Prof. Liliya Yatsunyk, Deondre Jordan '19, Samantha Nyovanie, Linda Lin '20 and Allan Gao '19, at the Haverford Undergraduate Research Symposium

Yatsunyk Lab Summer 2017

Summer 2017: Allan Gao '19, Barrett Powell '18, Prof. Liliya Yatsunyk, Deondre Jordan '19, and  Linda Lin '20 

Supriya Davis '16, Josh Turek-Herman '16, Prof. Liliya Yatsunyk, Joo Hyun Lee '17, Kara Bledsoe '16, and Jessica Chen ‘17

Summer 2012: Cole Harbeck '15, Vienna Tran ‘13, Steven Barrett 13, Michelle Ferreira '14, and Navin Sabharwal '14

Enjoying beautiful weather and roses: Samantha Nyovanie, Ariana Yett '21, Hyun Kyung Lee '21, Deondre Jordan '19, Dr. Liliya Yatsunyk, Yanti Manurung '20,  Linda Lin '20

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