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Kathryn Riley

Assistant Professor

On leave 2021-2022

Analytical Chemistry


  2. Phone: (610) 690-3904
  3. Martin Hall 207
Kathryn Riley


B.A., Chemistry, Swarthmore College

Ph.D., Chemistry, Wake Forest University

NRC Postdoctoral Fellow, National Institute of Standards and Technology (NIST)


Chem 10 (Foundations of Chemical Principles)

Chem 43 (Analytical Methods and Instrumentation)


Research in my group involves the development of analytical techniques for the characterization of nanomaterials and their dynamic transformations in biological and environmental matrices. Specifically, we are developing a suite of in situ electrochemical, spectroscopic, and separation technologies to monitor and quantify silver nanoparticle (AgNP) dissolution, aggregation, and protein corona formation. We are also applying these techniques to understand how AgNPs that are incorporated into consumer products (e.g., clothing fabrics) may be released during use of the product (e.g., wearing or washing the clothing).

Recent publications:

*undergraduate coauthor

Boehmler, D.J.*, O’Dell, Z.J.*, Chung, C.*, Riley, K.R. Bovine serum albumin enhances silver nanoparticle dissolution kinetics in a size- and concentration-dependent manner. Langmuir, 36 (2020) 1053-1061. doi:10.1021/acs.langmuir.9b03251

Hui, J.*, O’Dell, Z.J.*, Rao, A.*, Riley, K.R. In situ quantification of silver nanoparticle dissolution kinetics in simulated sweat using linear sweep stripping voltammetry. Environmental Science & Technology, 53 (2019) 13117-13125. doi:10.1021/acs.est.9b04151

Riley, K.R., El Hadri, H., Tan, J., Hackley, V.A., MacCrehan, W.A. High separation efficiency of gold nanomaterials of different aspect ratio and size using capillary transient isotachophoresis. Journal of Chromatography A, 1598 (2019) 216-222. doi:10.1016/j.chroma.2019.03.054

Riley, K.R., Sims, C.M., Wood, I.T., Vanderah, D.J., Walker, M.L. Short-chained oligo(ethylene oxide)-functionalized gold nanoparticles: realization of significant protein resistance. Analytical and Bioanalytical Chemistry, 410 (2018) 145-154. doi:10.1007/s00216-017-0704-0

Sims, C.M., Hanna, S.K., Heller, D.A., Horoszko, C.P., Johnson, M.E., Montoro Bustos, A.R., Reipa, V., Riley, K.R., Nelson, B.C. Redox-active nanomaterials for nanomedicine applications. Nanoscale, 9 (2017), 15226-15251doi:10.1039/C7NR05429G

Nelson, B.C., Johnson, M.E., Walker, M.L., Riley, K.R., Sims, C.M. Antioxidant cerium oxide nanoparticles in biology and medicine. Antioxidants, 5 (2016) 15. doi:10.3390/antiox5020015