Kathleen Howard
Edward Hicks Magill Professor of Mathematics & Natural Sciences
Chemistry & Biochemistry
Contact
Links
Affiliations: Provost's Office, Chemistry & Biochemistry
Education
A.B., Chemistry, Princeton University
Ph.D., Chemistry, Yale University
Postdoctoral Fellow, Chemistry, University of Pennsylvania
Dr. Howard teaches at all levels of the curriculum including physical chemistry, integrated experimental chemistry, introductory chemistry, and advanced topics seminars in biophysical chemistry. The research in her lab uses a range of physical methods to investigate the structural and dynamic properties of membrane-bound molecules. For more details, see the Howard Lab Research site.
Recent publications *Undergraduate co-author
Roepke, K.C.*, and Howard K.P. (2025) Conformation and Membrane Topology of the N-Terminal Ectodomain of Influenza A M2 Protein. Membranes 2025, 15(2), 40.
Kyaw, A.*, Roepke K.*, Arthur, T.* and Howard, K.P. (2023) Conformation of influenza AM2 membrane protein in nanodiscs and liposomes. Biochimica et Biophysica Acta- Biomembranes, 1865.
Kim G.*, Raymond, H.E.*, Herneisen, A.L.*, Wong-Rolle, A.* and Howard, K.P. (2019) The distal cytoplasmic tail of the influenza A M2 protein dynamically extends from the membrane. Biochimica Biophysica Acta – Biomembranes, 1861, 1421-1427.
Crouch, C., Bost, M.*, Kim, T.*, Green, B.*, Arbuckle, D.S.*, Grossman, C. and Howard, K.P. (2018) Optimization of Detergent-Mediated Reconstitution of Influenza A M2 Protein into Proteoliposomes. Membranes, 8, 103.
Herneisen, A.L.*, Sahu, I.D., McCarrick, R.M., Feix, J.B., Lorigan, G.A. and Howard, K. P. (2017) A Budding-Defective M2 Mutant Exhibits Reduced Membrane Interaction, Insensitivity to Cholesterol, and Perturbed Interdomain Coupling. Biochemistry, 56, 5955.
Kim, S.*, Upshur, M.A.*, Saotome, K.*, Sahu, I.D., McCarrick, R.M., Feix, J.B., Lorigan, G.A. and Howard, K. P. (2015) Cholesterol dependent conformational exchange of the C-terminal domain of the influenza A M2 protein. Biochemistry, 2015, 54 (49), 7157.
Huang, S.*, Green, B.,* Thompson, M.*, Chen, R.*, Thomaston, J., DeGrado, W. and Howard, K.P. (2015) C-terminal juxtamembrane region of the full-length M2 protein forms a membrane surface associated amphipathic helix. Protein Science, 24, 426. (selected as a "Highlight" of the issue by the journal editors)
