Publications

Detection of drug-induced conformational change of a transmembrane protein in lipid bilayers using site-directed spin labeling. Thomaston, J.L. Nguyen, P.A., Brown, E. C., Upshur, M.A. ,Wang, J. DeGrado, W.F. and Howard, K. P. (2013) . Protein Science, 22 (1): 65-73. (selected as a "Highlight" of the issue by the journal editors)

pH-Induced Conformational Change of the Influenza M2 Protein C-Terminal Domain. Nguyen, P.A., Soto, C., Polishchuk, A., Caputo,G., Tatko, C., Ma, C., Ohigashi, Y., Pinto, L.H. DeGrado, W.F. and Howard, K.P. (2008) Biochemistry, 47, 9934-9936.

Probing the phase behavior of membrane bilayers using 31P NMR Spectroscopy. Zee, B. and Howard, K.P. (2007) in Modern Nuclear Magnetic Resonance in Undergraduate Education, Edited by D. Rovnyak and R. Stockland, Jr. American Chemical Society Symposium Series, Oxford University Press.

The conformation of the pore region of the M2 proton channel depends on lipid bilayer environment. Duong-Ly, K., Nanda, V., DeGrado, W., and Howard K.P. (2005) Protein Science, 14, 856-861.

Rotational orientation of monomers within a designed homo-oligomer transmembrane helical bundle. Howard, K.P., Liu, W., Crocker, E., Nanda, V., Lear, J., DeGrado, W.F., and Smith, S.O. (2005) Protein Science, 14, 1019-1024.

Sequence determinants of the energetics of folding of a transmembrane four-helix-bundle protein. Howard, K.P., Lear, J.D., and DeGrado, W.F. (2002) Proceedings of the National Academy, 99(13), 8568-8572.

NMR study of doxorubicin binding to cardiolipin containing magnetically oriented phospholipid bilayers. Parker, M., King, V. and Howard, K.P. (2001) Biochimica Biophysica Acta; Biomembranes, 1514(2), 206-216.

Investigating Magnetically Aligned Phospholipid Bilayers with EPR Spectroscopy at 94 GHz. Mangels, M., Harper, A., Smirnov, A.I., Howard, K.P. and Lorigan, G.A. (2001) Journal of Magnetic Resonance, 151, 253-259.

Magnetically Aligned Phospholipid Bilayers at the Parallel and Perpendicular Orientations for X-Band Spin-Label EPR Studies. Cardon, T.B., Tiburu, E., Padmanabhan, A., Howard, K.P. and Lorigan, G.A. (2001) Journal of the American Chemical Society; 123(12), 2913-2914.

Spectroscopic Characterization of Spin Labeled Magnetically Oriented Phospholipid Bilayers by EPR Spectroscopy. Mangels, M., Cardon, T., Harper, A. Howard, K.P. and Lorigan, G.A. (2000) Journal of the American Chemical Society, 122(29), 7052-7058. .

Thermodynamics of DNA Duplex Formation. Howard, K.P. (2000) Journal of Chemical Education, 77(11), 1469-1471.

Pegylation of Magnetically Oriented Lipid Bilayers. King, V. , Parker, M. and Howard, K.P (2000) Journal of Magnetic Resonance, 142 (1), 177-182.

Magnetically Oriented Phospholipid Bilayers for Spin Label EPR Studies. Garber, S.M., Lorigan, G.A., and Howard, K.P. (1999) Journal of the American Chemical Society, 121, 3240-3241.

High Resolution Solid State NMR of Integral Membrane Proteins Reconstituted into Magnetically Oriented Phospholipid Bilayers. Howard, K.P. & Opella, S.J. (1996) Journal of Magnetic Resonance, 112, 91-94.

Conformation of Sulfoquinovosyl Diacylglycerol at the Surface of Magnetically-Oriented Phospholipid Bilayers. Howard, K.P. & Prestegard, J.H. (1996), Biophysical Journal, 71, 2573-2582.

Conformation and Dynamics of Digalactosyl Diacylglycerol. Howard, K.P. & Prestegard, J.H. (1996) Journal of the American Chemical Society, 118, 3345-3353.

Conformation of Monogalactosyl Diacylglycerol at the Surface of Magnetically-Oriented Phospholipid Bilayers. Howard, K.P. & Prestegard, J.H. (1995) Journal of the American Chemical Society, 117, 5031-5040.

Electrostatic Forces Contribute to Interactions Between trp repressor Dimers. Martin, K.S., Royer, C.A., Howard, K.P., Carey, J., Liu, Y., Matthews, K., Heyduk, E., Lee, J.C. (1994) Biophysical Journal, 66, 1167-1173.

NMR studies of ubiquinone location in oriented model membranes: Evidence for a single motionally-averaged population. Metz, G., Howard, K.P., van Liemt, W.B.S., Prestegard, J.H., Lugtenburg, J., & Smith, S.O. (1994) Journal of the American Chemical Society, 117, 564-565.

Magnetically-Oriented Phospholipid Micelles as a Tool for the Study of Membrane-Associated Molecules. Sanders, C.R., Hare, B., Howard, K.P., & Prestegard, J.H. (1993) Progress in NMR Spectroscopy, 26(5), 421-444.

Torsion Angle Analysis of Glycolipid Order at Membrane Surfaces. Hare, B.J., Howard, K.P., & Prestegard, J.H. (1993) Biophysical Journal 64, 392-398.

Three Dimensional 13C-13C Correlated Experiments on Oligosaccharides. Chung, J., Tolman, J.R., Howard, K.P., & Prestegard, J.H. (1993) Journal of Magnetic Resonance B., 102, 137-147.

Three Dimensional 1H-Detected 13C-13C Correlation Experiments for Carbon Backbone Assignments of Enriched Natural Products. Gosser, Y., Howard, K.P., & Prestegard, J.H. (1993) Journal of Magnetic Resonance B, 101, 126-133.