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Christopher Henkels



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Postdoctoral Associate, University of Virginia
Ph.D., Biochemistry, Duke University
M.S., Biochemistry, Cornell University
B.A., Chemistry, Colgate University


I will be teaching in the General Chemistry (CHEM 010 lab and CHEM 003) and Biochemistry (CHEM 108 and CHEM 038 lab) curriculums.

Research Interests

My research focuses on the consequences of protein-ligand interactions. Using biophysical techniques (including fluorescence spectroscopy, isothermal calorimetry, NMR and mass spectroscopy), we probe the structural, thermodynamic and motional consequences of binding between proteins and their binding partners.

Recent Publications

Henkels CH, Chang YC, Chamberlin SI, Oas TG. (2007) "Dynamics of Backbone Conformational Heterogeneity in Bacillus subtilis Ribonuclease P Protein." Biochemistry, 46(51): 15062-15075.

Henkels CH and Khorasanizadeh S. (2007) "Implications of a Histone Code Mimic in Epigenetic Signaling." Mol. Cell, 27(4): 521-522.

Henkels CH and Oas TG. (2006) "Ligation-State Hydrogen Exchange: Coupled Binding and Folding Equilibria in Ribonuclease P Protein." J. Am. Chem. Soc., 128(24): 7772-7781.

Henkels CH and Oas TG. (2005) "Thermodynamic Characterization of the Osmolyte- and Ligand-Folded States of Bacillus subtilis Ribonuclease P Protein." Biochemistry, 44(39): 13014-13026.