TBIC

Tri-college Bioinorganic Chemistry

The T-BIC consists of Rob Scarrow's research group from Haverford, Sharon Burgmayer's group from Bryn Mawr, and Liliya Yatsunyk's group from Swarthmore. Our group was initiated through Mellon Seed grants in 2009. We meet about 5 times a year on any of the campuses for joint group meetings where students have the opportunity to share their research findings with their peers and to troubleshot thier problems in collaborative environment. Once a year, we invite one well-respected bioinorganic speaker to give a presentation at one of our campuses. This presentation is usually accompanied by small poster session that facilitates communicaiton.

During the 2009-2010 academic year Professor Veronika Szalai from University of Maryland, Baltimore County was the first T-BIC sponsored speaker; she gave a research seminar on interactions of copper and the amyloid-beta peptide related to Alzheimer's disease at Haverford. In 2010-2011 academic year Professor Charles Riordan of the University of Delaware gave a TBIC presentation at Bryn Mawr. Prof. Riordan's seminar described his research group's efforts to create functional models of oxygenase enzymes using coordination complexes of nickel.

TBIC meeting on October 22, 2012 at Swarthmore College

22 students and faculty from Yatsunyk, Scarrow, and Burgmayer groups met at Haverford College talk about research and the exciting world of bioinorganic chemistry. Attendees enjoyed the following presentations:

  1. Michelle Ferreira (undergraduate, Swarthmore)
    Synthesis and Preliminary Characterization of Novel Polyamide Derivatives of Protoporphyrin IX and Mesoporphyrin IX
  2. Ben Williams (graduate student, Bryn Mawr)
    Structure and Reversible Pyran Formation in Molybdenum Pyrano-terin Dithioline Models of the Molybdenum Cofactor

TBIC meeting on June 6, 2012 at Swarthmore College

19 students and faculty from Yatsunyk's, Scarrow's, and Burgmayer's groups convened to present and discuss exciting research. The following presentations were given:

  1. Steven Barrett (undergraduate, Swarthmore)
    Structural Considerations of the NMM-Tel22 Complex
  2. Alexandra and Juliana (undergraduates, Bryn Mawr)
    Synthesis and Characterization of Ruthenium Complexes with dppz Ligands
  3. Jolie Krooks (undergraduate, Haverford) Isothiocyanato Co(II) and Cu(II) Complexes of Four Coordinate Tripodal Ligand (FCTC) with Conformational Binding Pocket

TBIC meeting on April 3, 2012 at Bryn Mawr College

Students and faculty from Yatsunyk's, Scarrow's and Burgmayer's groups gathered together for research discussions. The following talks were presented:

  1. Rob Scarrow and Jeff Schneider (undergraduate, Haverford)
    [Co(DIG3tren)X]X, where X = OAc, SCN, OCN, N3, Cl, F, and benzoate
  2. Navin Sabharwal (undergraduate, Swarthmore)
    Investigating the interactions between a platinum(II) metalloporphyrin and quadruplex DNA [pdf]
  3. Doug Giseqhite (graduate student), Yichun Fu, Hannah Gilbert, Suyin Lee (undergraduates, Bryn Mawr)
    Modeling the Molybdenum Cofactor

TBIC meeting on April 3, 2012 at Bryn Mawr College

TBIC meeting on February 7, 2012 at Swarthmore College

18 students and faculty from Yatsunyk's, Scarrow's and Burgmayer's groups gather together in the evening of February 7 to hear updates of each others research. The following talks were presented:

  1. Ben Williams (graduate student, Bryn Mawr)
    Investigations of BMOPP Chemisry: Modeling of the Mo cofactor
  2. Kevin D'aqilla (undergraduate, Haverford)
    Ni(II) complex with DIG3 TREN: potential oxidative catalysis and reactivity
  3. Cole Harbeck and Vienna Tran (undergraduates, Swarthmore)
    Stabilization of G-Quadruplex DNA by FRET [pdf]

TBIC meeting on February 7, 2012 at Swarthmore College