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This lab has three purposes. Our primary objective is to observe the later stage effects of a single exposure of ethanol to chicks early in development. We will look for phenotypic anomalies and compare our results to previous research. Second, we explore whether a dose dependence exists in the morphological effects of FAS. Previous work has not presented a conclusive model for dose dependence of a single injection of ethanol. We expect to see greater malformations with increased concentrations of ethanol. Our third goal is to investigate whether effects are dependent on the time of treatment. We expect to see greater extent of malformations in embryos that were treated with ethanol during a "critical window" of sensitivity at between 18-36 hours into development, when the cranial NCC are emigrating.

©Cebra-Thomas, 2000

Last Modified: 10 May 2004

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