CURRICULUM VITAE
Department of Biology
University of Pennsylvania
Philadelphia, PA 19104
(215) 898-2683 or (215) 898-5599
EDUCATION
1979-1986 Washington University,
St. Louis, MO Ph.D. Biology and Biomedical
Sciences 1975-1979 The Johns Hopkins
University, Baltimore,
MD B.A. Biology
APPOINTMENTS AND RESEARCH EXPERIENCE
2001 - present Lecturer, Departments of Biology
and Dermatology, University of Pennsylvania, Philadelphia,
PA 1997 -2001 Assistant Professor,
Department of Biology, Franklin &
Marshall College, Lancaster, PA Jan-July 1997 Research Associate,
Department of Biology, University of
Pennsylvania, Philadelphia, PA 1995-1996 Visiting Assistant
Professor, Department of
Biology, Swarthmore College, Swarthmore, PA 1994- 1995 Lecturer, Department
of Molecular Biology, Princeton University, Princeton,
NJ 1989- 1994 Research Staff Member,
Department of Molecular Biology,
Princeton University, Princeton, NJ 1986-1989 Postdoctoral Fellow Supervisor: Lee
M. Silver, Ph.D., Department of Molecular Biology,
Princeton University, Princeton, NJ 1979-1986 Graduate Research Assistant
Advisor: Joseph M. Davie, M.D., Ph.D., Department of Microbiology and
Immunology,Washington University, St. Louis, MO
AWARDS AND FELLOWSHIPS
1986-1989 American Cancer Society Postdoctoral Fellowship
1979-1982 National Science Foundation Predoctoral Fellowship
TEACHING EXPERIENCE
Spring '02 Developmental Biology (U.
Penn) Fall '97 -Th Spring '01 Physiology
& Development of Plants &
Animals, Developmental
Biology
(F&M) Fall 1995- Fall 1996 Embryology,
Developmental Genetics, Senior Evolution Seminar
(Swarthmore) 1994- Spring 1995 Director, Senior Project Lab
(Princeton) Summer 1990, 1991 Session Leader, Summer Research
Discussion Group (Princeton) Fall 1989, 1990 Session Leader, Junior Tutorial
(Princeton)
PROFESSIONAL SOCIETIES
Member, American Society for Cell Biology
Member, Society for Developmental Biology
Member. Sigma Xi
Recent presentations at professional meetings
Cebra-Thomas, J. A., J. Bromer*, H. Sheipe*, and S.F. Gilbert (1997). Role of the Tbx gene family in mesenchymal control of lung epithelial branching. Developmental Biology 186: 332. Presented at the Annual Meeting for the Society for Developmental Biology, July 1997
Cebra-Thomas J.A., J. Bromer*, G.K. Lam*, H. Sheipe* and S. F. Gilbert (1998) Role of the Tbx gene family in mesenchymal control of lung epithelial branching. Molecular Biology of the Cell, 9: 308a. Presented at the Annual Meeting for the American Society for Cell Biology, Dec. 12-16, 1998.
Cebra-Thomas, J.A., R. Shearman*, and V.A. Oropeza* (1999). A feedback loop between SHH and FGF8 may be involved in craniofacial development in the chick, Molecular Biology of the Cell, presented at the Annual Meeting for the American Society for Cell Biology, Dec. 11-15, 1999.
Oropeza*, V.C., A.A. Ligas* and J.A. Cebra-Thomas (2000) SHH signaling is required for feather bud development, Developmental Biology, 222: 252, presented at the annual meeting of the Society for Developmental Biology, Boulder, Co, June 7-11, 2000.
Ambeskovic*, I., J. Mendrola, J.A. Billet*, K. Huebner and J. A. Cebra-Thomas (2000) Protein tyrosine phosphatase gamma (PTPg) is required for primitive hematopoesis in the chick, Molecular Biology of the Cell, presented at the Annual Meeting for the American Society for Cell Biology, Dec. 9-13, 2000.
Rowan*, A.J., and J.A. Cebra-Thomas (2001) SHH and lung branching morphogenesis, presented at the Northeast Regional Meting of the Society for Developmental Biology, April 27-29, 2001.
(* denotes undergraduate co-author)
Publications
1. Clevinger, B., Thomas, J., Davie, J., Schilling, J., Bond,M., and Hood, L. (1981). Anti-dextran antibodies: sequences and idiotypes, in Immunoglobulin Idiotypes , Janeway, C., Sercarz, E., and Wigzell, H. (Eds.). Academic Press, New York , pp.159-168.
2. Cebra-Thomas, J., and Davie, J. (1984). AL-2: a new marker of activated lymphocytes. J. Cell Biochem. Suppl. 8A: 133.
3. Cebra-Thomas, J., Wagman, I., and Davie, J.M. (1985). AL-2 expression is a marker of activation of T and B cells. Fed. Proc. 44:1527.
4. Fyfe, G., Cebra-Thomas, J.A., Mustain, E., Davie, J.M., Alley, C.D., and Nahm, M.H. (1987). Subpopulations of B lymphocytes in germinal centers. J. Immunol. 139: 2187-2194.
5. Monafo, W.J., Greenspan, N.S., Cebra-Thomas, J.A., and Davie, J.M. (1987). Modulation of the murine immune response to streptococcal group A carbohydrate by inmmunization with monoclonal anti-idiotypes. J.Immunol. 139: 2702-2707.
6. Cebra, J.J., Cebra, E.R., Cebra-Thomas, J.A., George, A., Lebman, D.A., London, S.D., Rubin, D.H., and Schweitzer, P.A. (1988). Specific and nonspecific perturbations of B- and T-cell subsets in Peyer's patches. Monogr. Allergy 24: 173-180.
7. Cebra, J.J., Cebra-Thomas, J.A., Cuff, C.F., George, A., Kost, S.I., London, S.D., and Rubin, D.H. (1988). Reoviruses as probes of the gut mucosal T cell population, in Immunology and Immunopathology of the Alimentary Canal.
8. Schimenti, J., Cebra-Thomas, J.A., Decker, C.L., Islam*, S.D., Pilder, S.H., and Silver, L.M. (1988). A candidate gene family for the mouse t complex responder (Tcr) locus responsible for haploid effects on sperm function. Cell 55: 71-78.
9. Brown*, J., Cebra-Thomas, J.A., Bleil, J.D., Wassarman, P.M., and Silver, L.M. (1989). A premature acrosome reaction is programmed by mouse t haplotypes during sperm differentiation and could play a role in transmission ratio distortion. Development 106: 769-773.
10. London, S.D., Cebra-Thomas, J.A., Rubin, D.H., and Cebra, J.J. (1990). CD8 lymphocyte subpopulations in Peyer's patches induced by reovirus serotype 1 infection. J. Immunol., 144: 3187-3194.
11. Cebra-Thomas, J.A., and Silver, L.M. (1991). Genetic aspects of sperm differentiation and function in the mouse. Elements of Mammalian Fertilization, Vol.1, Wassarman, P. M. (editor), CRC Press, New York, pp. 29-56.
12. Cebra-Thomas, J.A., Snyder, L., Decker, C.L., Pilder, S.H., and Silver, L.M. (1991) Allele- and haploid-specific product generated by alternative splicing from a mouse t complex responder locus candidate. Nature 349: 239-241.
13. Weinstein, P.W., Schweitzer, P. A., Cebra-Thomas, J.A., and Cebra, J.J. (1991) Molecular genetic features reflecting the preference for isotype switching to IgA expression by Peyer's patch germinal center cells. Int. Immunol. 3:1253-1263.
14. Platt, F.M., Cebra-Thomas, J.A., Baum, C.M., Davie, J.M., and McKearn, J.P. (1992) Monoclonal antibodies specific for novel murine cell surface markers define subpopulations of germinal center cells. Cell. Immunol. 143:449-466.
15. Pilder, S.H., Decker, C.L., Islam*, S.D., Buck, C., Cebra-Thomas, J.A., and Silver, L.M. (1992) Concerted evolution of the mouse Tcp-10 gene family: implications for the functional basis of t haplotype transmission ratio distortion. Genomics 12: 35-41.
16. Cebra-Thomas, J.A., Tsai, J.-Y., Pilder, S.M., Copeland, N., Jenkins, N., and Silver, L.M. (1992) Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting. Genomics 13: 444-446.
17. Islam*, S., Pilder, S.H., Decker, C.L., Cebra-Thomas, J.A., and Silver, L.M. (1993). The human homolog of a candidate mouse t complex responder gene: conserved motifs and evolution with punctuated equilibria, Human Mol. Gen. 2:2075-2079.
18. Bollag, R. J., Siegfried, Z., Cebra-Thomas,J. A., Davidson*, E. M., and Silver, L M. (1994) An ancient family of embryonically expressed mouse genes with a shared T locus motif, Nature Gen. 7:383-389.
19. Chapman, D.L., Garvey, N., Hancock*, S., Alexiou, M., Agulnik, S., Gibson-Brown, J.J., Cebra-Thomas, J.A., Bollag, R.J., Silver, L.M., and Papaioannou, V.E. (1996) T-box family gene expression during inductive interactions in early mouse development. Developmental Dynamics, 206: 379-390.
20. Cebra-Thomas J.A., Brommer*, J., Gardner*, R J., Lam*, G.K., Sheipe*, H.,A., and Gilbert, S.F. (2003) T-box gene products are required for mesenchymal induction of epithelial branching in the embryonic mouse lung, Developmental Dynamics, 226: 82-90.
21. Ligas*,A.A., Oropeza*,V.C., and Cebra-Thomas, J.A., A combination of SHH and FGF4 signaling is required for feather bud elongation, in preparation.
22. Cebra-Thomas, J.A., Rowan*, A.J., and De Long*, J.K., FGF signaling is required for initiation but not outgrowth of lung branches, in preparation.
23. Mendrola, J., Ambeskovic*, I., Billet*, J.A., Gilbert, S.F., Huebner, K., and Cebra-Thomas, J.A., Expression of receptor tyrosine phosphatase g, Ptpg, is essential for blood island formation in early chick embryos, in preparation
24. Shearman*,R., Fleming*, J. K., and Cebra-Thomas, J.A., The role of SHH and FGF8 in craniofacial development in the chick, in preparation.
(* denotes undergraduate co-author)