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		Dorsal Lip Transplant in Amphibian Embryos Marie Nickle, Franklin and Marshall College, Class of 2001 Introduction In early stages of development in amphibian embryos, very few cells' fates are rigidly determined. However, previous experiments show that cells in one area of the developing embryo are determined before gastrulation. This area in the amphibian embryo has since been termed the organizer for its role in cell fate determination. In 1924 Hans Spemann and Hilde Mangold showed that cells transplanted from this "organizer" region of the blastopore lip of one embryo will induce gastrulation in any kind of tissue. They used this information to induce the growth of a second neural tube on an already developing embryo. This experiment attempts to repeat Spemann and Mangold's experiment in Xenopus embryos. *Modified from: Johnson, Leland G. Johnson & Volpes Patterns & Experiments in Developmental Biology. McGraw-Hill Co. Incorporated: Dubuque, IA. 1999 p.53-58