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Developmental Genetics

Judith Cebra-Thomas

Fall 2003

Human development: cloning, stem cells and tissue engineering

The seminar will focus on the therapeutic applications of developmental biology. We will focus on early development and cloning, organogenesis and tissue engineering, and the isolation, differentiation and potential uses of adult and embryonic stem cells. The laboratory will consist of an introduction to techniques used to study and manipulate gene expression in chicks and mammals, and then of group projects involving some aspect of cell differentiation or organogenesis.

Required reading:

Gilbert, Scott, Developmental Biology, 7th edition, Sinauer Press 2003

Kolata, Gina, Clone: the Road to Dolly, and the Path Ahead, William Morrow, 1998

Silver, Lee, Remaking Eden: Cloning and Beyond in a Brave New World,
Avon Books, 1997; pp. 1-11, 91-130

Andrew, Lori, The Clone Age,



Moody, Sally, Cell Lineage and Fate Determination, Academic Press 1999