Figure 23-17

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X-ray structure of human dihydrofolate reductase in complex with folic acid. The polypeptide is colored in rainbow order from its N-terminus (blue) to its C-terminus (red). The folic acid is drawn in space-filling form with C green, N blue, and O red. [Based on an X-ray structure by Joseph Kraut, University of California at San Diego. PDBid 1DHF.]