Education:
Honors Diploma, Chernivtsi State University, Ukraine
Ph.D., University of Arizona
Postdoctoral Fellow, Northwestern University
Contact information:
Science Center 286
Telephone: (610) 328-8558
FAX: (610) 328-7355
Electronic mail: lyatsun1@swarthmore.edu
Mailing address: Department of Chemistry and Biochemistry, Swarthmore College,
500 College Avenue, Swarthmore, PA 19081- 1397
My laboratory focuses on the design, synthesis,
and characterization of novel porphyrin-based antitumor drugs that function
via inhibition of telomerase. The students will be exposed to various aspects
of bioinorganic chemistry. They will get an opportunity to gain knowledge
and experience in a broad range of techniques with multiple applications.
These include basic and advanced synthetic skills, DNA manipulation, small
molecule crystallization, biochemical assays, collection/analysis of crystallographic
data, and application of spectroscopic techniques to characterization of
porphyrin and porphyrin-DNA interactions. The long term goal of the research
is to develop better porphyrin-based anticancer therapeutics.
My teaching responsibilities typically include a combination of Inorganic
Chemistry (Chemistry 46), General Chemistry (Chemistry 10 and 10H) as well
as advanced topics in Biological Inorganic Chemistry (Chemistry 106).