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Biology 001:  Cellular and Molecular Biology

This is a team-taught fall semester course targeted at both majors and non-majors, in which each of 4 faculty members gives 8-9 lectures.   Weekly laboratory sections are led by faculty - I teach the same 20-25 students in the weekly laboratory for the entire fall semester.  I am assisted in the lab by a Laboratory Instructor and a senior biology major.

Writing assignments, quizzes and a final exam are the ways in which performance is assessed.  Knowledge of general principles and important concepts is demonstrated by application and analysis, rather than be memorization.

Biology 16 and 17:

These are courses that I teach in alternation in the spring semester.  Students may take one or the other, but not both courses.  The primary reason for this restriction is that the laboratory portions of the 2 courses are identical.  Standard microbiological techniques are introduced in the laboratory, which is open 24 hours.  Students are expected to follow up on experiments outside of the formal laboratory period. It is the lecture content of the two that differs.  Evaluation of student performance includes essay exams, short writing assignments, laboratory write-ups, oral presentations and a laboratory practical.

Biology 16 is Microbiology

This course, with its weekly laboratory, focuses on general areas of microbiology including: bacterial structure and function; metabolism and physiology,;bacterial genetics and regulation of gene expression; growth and control of growth; evolution of life on earth; ecology and nutrient cycling; symbiosis and unique niches (extremophiles); viruses; systematics and taxonomy; antibiotics and resistance; industrial and food microbiology; and a brief introduction to immunity and immunochemistry.

Biology 17 is Microbial Pathogenesis and the Immune Response, This is a course that I designed so that I could teach about co-evolutionary mechanisms. Some of the topics overlap with Biology 16 (and the weekly lab is identical), but many lectures emphasize the interactions of hosts and pathogens: bacterial structure and function; metabolism and physiology; bacterial genetics and regulation of gene expression; viruses; antibiotics and resistance; symbiosis and pathogenicity; innate immunity; T cells and the MHC; B cells and the antibody response; virulence mechanisms; vaccines; molecular diagnostics and immunochemistry.

Biology 116 is Microbial Processes and Biotechnology

Over the years, this honors seminar, in which students read and present the primary literature, has evolved from a course in advanced bacterial genetics to one on advanced bacterial physiology and metabolism.  In fact, we still learn a great deal of bacterial genetics, but do so now in the context of metabolic complexity.  Students become familiar with many biochemical pathways of intermediary metabolism and learn why these are interesting areas of investigation in the fields of pathogenesis, microbial ecology and evolution, pharmacology, enzymology and basic bacterial physiology.  Students also conduct independent research projects in small groups.  Additionally, each student writes an extensive research proposal on a biological problem that affects a third world country and outlines a biotechnological solution.  Students gain experience with oral presentations, building a logical set of arguments, based on principles and precedence, writing short and long papers, use and proper citation of literature and participating in the peer-review process.  Students who complete Biology 16 or 17 with a minimum grade of B are encouraged to enroll.             

Since 1995, many honors students have stood for oral and written exams, given by external examiners, in Biology 116 (which used to have a different number: Biology 55).  External examiners come from microbiology programs at major colleges and universities.  They write a 3-hour, closed book exam based on the papers that students have read and presented in Biology 116.  Some examiners also are asked to evaluate honors theses.  Previous honors examiners in microbiology (seminar or thesis) have included: Yves Brun, Indiana University; Heidi Kaplan, University of Texas Medical School; Roberto Kolter, Harvard University; Stanley Maloy, University of Illinois, Urbana-Champaign; Mitchell Singer, University of California, Davis; Clay Fuqua, Indiana University; Joanne Willey, Hostra University; Nancy Love, Virginia Tech; Patrick Piggot, Temple University; Tony Lobo, Ursinus College.

Other Swarthmore courses that I have taught (but not on a regular basis)

Biology 5/Philosophy15: Biotechnology and Society: The Case of Agriculture

Team-taught in 1999 and 2000 with Professor of Philosophy Hugh Lacey (who has since retired)

This course was cross-listed in both departments, but did not satisfy major requirements in either.  It was weekly a 3-hour discussion with no lab.  It was billed as an introduction to biotechnology, as it pertained to the development of genetically modified organisms (GMOs) and to their uses in agriculture, and to related issues in the ethics and philosophy of science. Topics included: methods and possibilities of genetic engineering; ethical questions raised by research and development of GMOs for use in agriculture, and associated legal issues; risks that may be occasioned for consumer rights, human health, the environment and the maintenance of biodiversity; long-term conduct of agricultural practices for the sake of feeding the whole world: the growth of agribusiness and the struggle for alternative forms of agriculture to survive; patents/intellectual property rights and their effects on the conduct of science; third world perspectives.  Students were evaluated on presentations, participation in discussions and collaborative projects, and written work.  Enrollment was open to anyone with introductory biology (or AP credit) and one introductory philosophy course.

Unfortunately, I have not had a partner to co-teach this course since 2002.

Biology 93:  Directed Reading in Virology

This course is only available if 2 or more students, who have already completed Biology 16 or 17 with a minimum grade of B, are willing to meet with each other for 3 hours per week and with the instructor for an hour a week.  Reading material include virology texts as well as classical papers on bacteriophage lambda and the primary research literature.  Two extensive research papers on 2 different virus systems are required.  Each professor in Biology  has the option of offering Directed Reading courses in his/her area.  They are listed as separate sections of Biology 93.

Life Long Studies 122:  Why We Get Sick, or Not

This course is an adult education course that is offered as a part of the LLS program at Swarthmore.  Students in the course are local Swarthmore residents, alumni and friends of the College.  The course meets for 8 weeks, 2 hours per week, in the evenings.  Readings are based on a text by Williams and Nesse:  Why We Get Sick, literature published by the American Society for Microbiology for the public, as well as articles from current magazines and newspapers.  Students participate in discussions and have a brief presentation during one week.  It was offered in the spring of 2006 for the first time and may be offered again in 2008.

 


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